Hydroxyethyl-starch use and PBM. a necessary update to the italian national guidelines

Hydroxyethyl-starch use and PBM a necessary update to the italian national guideline

Structure, tools, discourse and practices: a multidimensional comparative approach to EU territorial governance

The concept of "EU territorial governance" has been recently adopted by planners and decision-makers to indicate the occurrence of a complex, multifaceted and largely undefined process of spatial planning and development activities guided, at various levels, in the European Union's institutional context. Building on a EU territorial governance conceptual framework elaborated by the authors in previous work, which individuates the specific „channels‟ of interaction that convey change in European countries, on the one hand, and institutional progress at the EU level, on the other hand, the contribution aims to shed some light on the differential impact exerted by such channels as they manifests in relation to different Member States domestic contexts. It does so by adopting three different national contexts as case studies, representative of as many „ideal types‟ of planning system traditions existing in Europe - namely , „comprehensive integrated‟ (Germany), „urbanism‟ (Italy), plus a supposed „Central and Eastern European socialist transition‟ type (Poland) - and providing a comparative analysis of the elements that, in relation to each of them, influence the evolution of European spatial planning and spatial planning domestic contexts within the complex framework of EU territorial governanc

A decomposition of the Jacobian of a Humbert-Edge curve

A \textit{Humbert-Edge curve of type} $n$ is a non-degenerate smooth complete intersection of $n-1$ diagonal quadrics. Such a curve has an interesting geometry since it has a natural action of the group $(\mathbb{Z}/2\mathbb{Z})^n$. We present here a decomposition of its Jacobian variety as a product of Prym-Tyurin varieties, and we compute the kernel of the corresponding isogeny.Comment: 9 pages, comments welcome! To appear in Contemporary Mathematic

Ontology-based model abstraction

In recent years, there has been a growth in the use of reference conceptual models to capture information about complex and critical domains. However, as the complexity of domain increases, so does the size and complexity of the models that represent them. Over the years, different techniques for complexity management in large conceptual models have been developed. In particular, several authors have proposed different techniques for model abstraction. In this paper, we leverage on the ontologically well-founded semantics of the modeling language OntoUML to propose a novel approach for model abstraction in conceptual models. We provide a precise definition for a set of Graph-Rewriting rules that can automatically produce much-reduced versions of OntoUML models that concentrate the models’ information content around the ontologically essential types in that domain, i.e., the so-called Kinds. The approach has been implemented using a model-based editor and tested over a repository of OntoUML models

When alarm bells ring: emergency tinnitus

OBJECTIVE: The aim of this study is to develop a diagnostic-therapeutic algorithm for those suffering from tinnitus who seek emergency aid. MATERIALS AND METHODS: A literature review has been performed on articles from the last 30 years. RESULTS: It is important to activate medical or surgical diagnostic and therapeutic strategies, in order to safeguard and rehabilitate the various functions affected. Psychiatric comorbidity is the most frequent pathological condition of those with serious or catastrophic tinnitus. In these cases, mortality risk is linked to suicide, morbidity to tinnitus-correlated distress. CONCLUSIONS: Tinnitus, mainly linked to loss of hearing, is a frequent symptom among the population at large. About 7% of those affected by tinnitus turn to their doctor to solve their problem, while between 0.5 and 2% request urgent medical assistance. Their cry for help may be the result of an acute onset of tinnitus or the rapid impairment of an already chronic condition. Tinnitus is not considered an urgent ear, nose and throat (ENT) condition by the Associazione Otorinolaringologi Ospedalieri Italiani (AOOI) [Italian Association of Hospital ENT], even though there are many pathological conditions, sometimes serious, associated with tinnitus and emergency action is necessary to reduce the risk of morbidity and mortality

How we treat bleeding associated with direct oral anticoagulants

Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the case of bleeding or emergency situations such as trauma, stroke requiring thrombolysis, and urgent surgery. The progressive development of antidotes for these new drugs, which, it is hoped, will become available in the near future, will allow better and safer management of the rapid reversal of their anticoagulant effect

Form factor in K+ --> pi+ pi0 gamma: interference versus direct emission

We analyze the effect of a form factor in the magnetic contribution to K+ --> pi+ pi0 gamma. We emphasize how this can show up experimentally: in particular we try to explore the difference between a possible interference contribution and a form factor in the magnetic part. The form factor used for K+ --> pi+ pi0 gamma is analogous to the one for KL --> pi+ pi- gamma, experimentally well established.Comment: 9 pages revtex, 10 eps figures; improved presentation of theoretical and experimental status; refs. adde

Zika virus and the never-ending story of emerging pathogens and transfusion medicine

In the last few years, the transfusion medicine community has been paying special attention to emerging vector-borne diseases transmitted by arboviruses. Zika virus is the latest of these pathogens and is responsible for major outbreaks in Africa, Asia and, more recently, in previously infection-naïve territories of the Pacific area. Many issues regarding this emerging pathogen remain unclear and require further investigation. National health authorities have adopted different prevention strategies. The aim of this review article is to discuss the currently available, though limited, information and the potential impact of this virus on transfusion medicine

A decentralized scalable approach to voltage control of DC islanded microgrids

We propose a new decentralized control scheme for DC Islanded microGrids (ImGs) composed by several Distributed Generation Units (DGUs) with a general interconnection topology. Each local controller regulates to a reference value the voltage of the Point of Common Coupling (PCC) of the corresponding DGU. Notably, off-line control design is conducted in a Plug-and-Play (PnP) fashion meaning that (i) the possibility of adding/removing a DGU without spoiling stability of the overall ImG is checked through an optimization problem; (ii) when a DGU is plugged in or out at most neighbouring DGUs have to update their controllers and (iii) the synthesis of a local controller uses only information on the corresponding DGU and lines connected to it. This guarantee total scalability of control synthesis as the ImG size grows or DGU gets replaced. Yes, under mild approximations of line dynamics, we formally guarantee stability of the overall closed-loop ImG. The performance of the proposed controllers is analyzed simulating different scenarios in PSCAD.Comment: arXiv admin note: text overlap with arXiv:1405.242

Softness dependence of the Anomalies for the Continuous Shouldered Well potential

By molecular dynamic simulations we study a system of particles interacting through a continuous isotropic pairwise core-softened potential consisting of a repulsive shoulder and an attractive well. The model displays a phase diagram with three fluid phases, a gas-liquid critical point, a liquid-liquid critical point, and anomalies in density, diffusion and structure. The hierarchy of the anomalies is the same as for water. We study the effect on the anomalies of varying the softness of the potential. We find that, making the soft-core steeper, the regions of density and diffusion anomalies contract in the T - {\rho} plane, while the region of structural anomaly is weakly affected. Therefore, a liquid can have anomalous structural behavior without density or diffusion anomalies. We show that, by considering as effective distances those corresponding to the maxima of the first two peaks of the radial distribution function g(r) in the high-density liquid, we can generalize to continuous two-scales potentials a criterion for the occurrence of the anomalies of density and diffusion, originally proposed for discontinuous potentials. We observe that the knowledge of the structural behavior within the first two coordination shells of the liquid is not enough to establish the occurrence of the anomalies. By introducing the density derivative of the the cumulative order integral of the excess entropy we show that the anomalous behavior is regulated by the structural order at distances as large as the fourth coordination shell. By comparing the results for different softness of the potential, we conclude that the disappearing of the density and diffusion anomalies for the steeper potentials is due to a more structured short-range order. All these results increase our understanding on how, knowing the interaction potential, we can evaluate the possible presence of anomalies for a liquid